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必赢bwin线路检测中心导师简介-李军

来源: 作者: 发布时间:2022-08-01

 

所属学科名称:中药化学

导师简介: 李军

 

个人简介(不多于350字):

博士、研究员、博士研究生导师。国家药典委员会委员,教育部新世纪优秀人才,获中华中医药学会中青年创新人才奖,现任必赢bwin线路检测中心副院长。兼任《必赢bwin线路检测中心学报》《中国中药杂志》《中草药》《中国医院用药评价与分析》编委,《Chinese Herbal Medicines》《Journal of Traditional Chinese Medical Sciences》《世界中医药》青年编委,中国中药协会精准中药专业委员会副主任委员。

联系方式:E-mail: drlj666@163.com

 

主要研究方向:

1. 中药药效物质与作用机理研究

2. 中药质量评价

 

科研成果(不多于350字):

主持承担了国家重点研发计划、国家重大新药创制、国家自然科学基金等国家和省部级课题19项。成果获得国家科学技术技进步二等奖1项(第三完成人),教育部高等学校科学研究优秀成果自然科学二等奖1项(第三完成人)。以第一或通讯作者发表论文114篇,其中在Org LettAnal ChemJ Adv ResJ Nat ProdSCI收录杂志发表论文75参编著作7部,获得授权中国发明专利20项。

代表性论文:

  1. Ma J#, Huo H#, Zhang H, Wang L, Meng Y, Jin F, Wang X, Zhao Y, Zhao Y, Tu P, Song Y*, Zheng J*, Li J*. 2-(2-Phenylethyl)chromone-enriched extract of the resinous heartwood of Chinese agarwood (Aquilaria sinensis) protects against taurocholic acid-induced gastric epithelial cells apoptosis through Perk/eIF2α/CHOP pathway. Phytomedicine 2022, 98, 153935.
  2. Qi B, Li N, Zhang B, Zhang Z, Wang W, Liu X, Wang J, Awakawa T, Tu P, Abe I*, Shi S*, Li J*. A multifunctional cytochrome P450 and a meroterpenoid cyclase in the biosynthesis of fungal meroterpenoid atlantinone B. Org Lett 2022, 24, 2526−2530.
  3. Liu W, Li W, Zhang P, Gong X, Tu P, Tang L*, Li J*, Song Y*. Quality structural annotation for the metabolites of chlorogenic acid in rat. Food Chem 2022, 379, 132134.
  4. Wang CC#, Liang NY#, Xia H, Wang RY, Zhang YF, Huo HX, Zhao YF, Song YL, Zheng J, Tu PF*, Li J*. Cytotoxic sesquiterpenoid dimers from the resin of Commiphora myrrha Engl.. Phytochenmistry 2022, 204, 113443.
  5. Zhu ZX#, Wang LL#, Guo R, Pang DR, Wang WX, Wu Y, Li J*, Tu PF*. XJ-8, a natural compound isolated from Sanguis draxonis, inhibits platelet function and thrombosis by targeting MAP3K3. J Thromb Haemost 2022, 20, 605–618.
  6. Pan B#, Sun J#, Liu ZY, Wang LX, Huo HX, Zhao YF, Tu PF, Xiao W, Zheng J*, Li J*. Longxuetongluo Capsule protects against cerebral ischemia/reperfusion injury through endoplasmic reticulum stress and MAPK-mediated mechanisms. J Adv Res 2021, 33, 215–225.
  7. Xu X, Li W, Li T, Zhang K, Song Q, Liu L, Tu P, Wang Y, Song Y*, Li J*. Direct infusion–three-dimensional mass spectrometry enables rapid chemome comparison among herbal medicines. Anal Chem 2020, 92, 7646–7656.
  8. Guan PW, Song QQ, Li T, Cao LB, Tang HT, Wang YT, Tu PF, Zheng J*, Song YL*, Li  J*. Confirmative structural annotation for metabolites of (R)-7,3'-dihydroxy-4'-methoxy-8-methylflavane, a natural sweet taste modulator, by liquid chromatography-three-dimensional mass spectrometry. J Agric Food Chem 2020, 68(44):12454-12466.
  9. Liu WJ, Song QQ, Cao Y, Zhao YF, Huo HX, Wang YT, Song YL*, Li J*, Tu PF. Advanced liquid chromatography-mass spectrometry enables merging widely targeted metabolomics and proteomics. Anal Chim Acta 2019, 1069, 89–97.
  10. Huo HX, Zhu ZX, Song YL, Shi SP, Sun J, Sun H, Zhao YF, Zheng J, Ferreira D, Zjawiony JK, Tu PF, Li J*. Anti-inflammatory dimeric 2-(2-phenylethyl)chromones from the resinous wood of Aquilaria sinensis. J Nat Prod 2018, 81, 543–553.