必赢bwin线路检测中心导师简介-李军
来源:
作者:
发布时间:2022-08-01
所属学科名称:中药化学
导师简介: 李军
个人简介(不多于350字):
博士、研究员、博士研究生导师。国家药典委员会委员,教育部新世纪优秀人才,获中华中医药学会中青年创新人才奖,现任必赢bwin线路检测中心副院长。兼任《必赢bwin线路检测中心学报》《中国中药杂志》《中草药》《中国医院用药评价与分析》编委,《Chinese Herbal Medicines》《Journal of Traditional Chinese Medical Sciences》《世界中医药》青年编委,中国中药协会精准中药专业委员会副主任委员。
联系方式:E-mail: drlj666@163.com
主要研究方向:
1. 中药药效物质与作用机理研究
2. 中药质量评价
科研成果(不多于350字):
主持承担了国家重点研发计划、国家重大新药创制、国家自然科学基金等国家和省部级课题19项。成果获得国家科学技术技进步二等奖1项(第三完成人),教育部高等学校科学研究优秀成果自然科学二等奖1项(第三完成人)。以第一或通讯作者发表论文114篇,其中在Org Lett,Anal Chem,J Adv Res,J Nat Prod等SCI收录杂志发表论文75篇;参编著作7部,获得授权中国发明专利20项。
代表性论文:
- Ma J#, Huo H#, Zhang H, Wang L, Meng Y, Jin F, Wang X, Zhao Y, Zhao Y, Tu P, Song Y*, Zheng J*, Li J*. 2-(2-Phenylethyl)chromone-enriched extract of the resinous heartwood of Chinese agarwood (Aquilaria sinensis) protects against taurocholic acid-induced gastric epithelial cells apoptosis through Perk/eIF2α/CHOP pathway. Phytomedicine 2022, 98, 153935.
- Qi B, Li N, Zhang B, Zhang Z, Wang W, Liu X, Wang J, Awakawa T, Tu P, Abe I*, Shi S*, Li J*. A multifunctional cytochrome P450 and a meroterpenoid cyclase in the biosynthesis of fungal meroterpenoid atlantinone B. Org Lett 2022, 24, 2526−2530.
- Liu W, Li W, Zhang P, Gong X, Tu P, Tang L*, Li J*, Song Y*. Quality structural annotation for the metabolites of chlorogenic acid in rat. Food Chem 2022, 379, 132134.
- Wang CC#, Liang NY#, Xia H, Wang RY, Zhang YF, Huo HX, Zhao YF, Song YL, Zheng J, Tu PF*, Li J*. Cytotoxic sesquiterpenoid dimers from the resin of Commiphora myrrha Engl.. Phytochenmistry 2022, 204, 113443.
- Zhu ZX#, Wang LL#, Guo R, Pang DR, Wang WX, Wu Y, Li J*, Tu PF*. XJ-8, a natural compound isolated from Sanguis draxonis, inhibits platelet function and thrombosis by targeting MAP3K3. J Thromb Haemost 2022, 20, 605–618.
- Pan B#, Sun J#, Liu ZY, Wang LX, Huo HX, Zhao YF, Tu PF, Xiao W, Zheng J*, Li J*. Longxuetongluo Capsule protects against cerebral ischemia/reperfusion injury through endoplasmic reticulum stress and MAPK-mediated mechanisms. J Adv Res 2021, 33, 215–225.
- Xu X, Li W, Li T, Zhang K, Song Q, Liu L, Tu P, Wang Y, Song Y*, Li J*. Direct infusion–three-dimensional mass spectrometry enables rapid chemome comparison among herbal medicines. Anal Chem 2020, 92, 7646–7656.
- Guan PW, Song QQ, Li T, Cao LB, Tang HT, Wang YT, Tu PF, Zheng J*, Song YL*, Li J*. Confirmative structural annotation for metabolites of (R)-7,3'-dihydroxy-4'-methoxy-8-methylflavane, a natural sweet taste modulator, by liquid chromatography-three-dimensional mass spectrometry. J Agric Food Chem 2020, 68(44):12454-12466.
- Liu WJ, Song QQ, Cao Y, Zhao YF, Huo HX, Wang YT, Song YL*, Li J*, Tu PF. Advanced liquid chromatography-mass spectrometry enables merging widely targeted metabolomics and proteomics. Anal Chim Acta 2019, 1069, 89–97.
- Huo HX, Zhu ZX, Song YL, Shi SP, Sun J, Sun H, Zhao YF, Zheng J, Ferreira D, Zjawiony JK, Tu PF, Li J*. Anti-inflammatory dimeric 2-(2-phenylethyl)chromones from the resinous wood of Aquilaria sinensis. J Nat Prod 2018, 81, 543–553.